ISSN:
1420-9071
Keywords:
Key words. Vitamin E; phospholipase A2; membrane stabilization.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract. This investigation shows the membrane stabilizing effect of α-tocopherol against the damaging action of viper venom phospholipase A2 (PLA2). Liver lysosomal membranes from rats fed 100 mg and 200 mg α-tocopherol acetate per kilogram of diet were more resistant to damage by viper venom PLA2 compared with vitamin E-deficient rats. The membrane stabilizing effect of vitamin E is proposed to be due to the formation of a complex with the phospholipid hydrolysis products of the membrane.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/PL00000586
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