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  • 1
    Digitale Medien
    Digitale Medien
    A tailgut cyst found accompanying rectal cancer: Report of a case (1995)
    Springer
    Surgery today 25 (1995), S. 65-67 
    Details
    ISSN: 1436-2813
    Schlagwort(e): tailgut cyst ; rectal cancer ; differential diagnosis ; retrorectal cyst
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Tailgut cysts are rare congenital lesions. To date, only four cases have been reported in Japan, and the occurrence of a tailgut cyst with rectal cancer has never been documented. We describe here the case of a patient in whom a tailgut cyst in the retrorectal space was associated with rectal cancer. Preoperative computed tomography scans and endorectal ultrasonography failed to identify the lesion as cystic, instead suggesting an involved lymph node. This case emphasizes the necessity for careful diagnosis of masses in the retrorectal space in patients with rectal cancer.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00309389
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  • 2
    Digitale Medien
    Digitale Medien
    Adenoid basal carcinoma of the uterine cervix: a case report with ultrastructural findings (2000)
    Springer
    Medical electron microscopy 33 (2000), S. 241-245 
    Details
    ISSN: 1437-773X
    Schlagwort(e): Key words Adenoid basal carcinoma ; Uterine cervix ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Adenoid basal carcinoma of the uterine cervix is a rare tumor with a favorable prognosis. A case of adenoid basal carcinoma (ABC) of the uterine cervix was studied using light and electron microscopy. The patient was a 74-year-old Japanese woman who had undergone hysterectomy due to cervical intraepithelial neoplasia 3. Incidentally, ABC was found in the resected uterus. The tumor cells made small nests and infiltrated the cervical portion of the uterus. In the nests, glands, cribriform patterns with glandlike structures, and squamous differentiation were seen. Immunohistochemically, the glandlike structures were positive for laminin and type IV collagen. Ultrastructurally, the tumor cells had irregular nuclei, scanty cytoplasm, and cribriform patterns in which glandlike structures were covered with basal lamina. No myoepithelial differentiation of the tumor cells was seen. These findings suggest a similarity between adenoid basal carcinomas and adenoid cystic carcinomas. Furthermore, both tumors are considered to originate in the reserve cells of the uterine cervix. Because their outcomes are different, they should be distinguished from each other.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s007950000024
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  • 3
    Digitale Medien
    Digitale Medien
    Expression of UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase isozymes T1 and T2 in human colorectal cancer (2000)
    Springer
    Journal of gastroenterology 35 (2000), S. 840-848 
    Details
    ISSN: 1435-5922
    Schlagwort(e): Key words: GalNAc transferase ; colorectal cancer ; mucin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract: Uridine diphosphate (UDP)-GalNAc: polypeptide N-acetylgalactosaminyltransferase (GalNAc transferase) catalyzes the initial step in mucin type O-glycosylation, and its expression has been assumed to be altered between normal epithelial cells and cancer cells. We studied the alteration of GalNAc transferase expression during the carcinogenesis of human colorectal epithelial cells. We produced polyclonal antibodies against synthetic polypeptides with specific sequence to two GalNAc transferase isozymes, T1 and T2. Surgically resected specimens from 50 patients with colorectal cancer were immunohistochemically stained, and the staining grade (percentage of positively stained cells) was compared between cancer and its normal counterpart in the same specimen. Significant signals for both T1 and T2 expression were seen in the supranuclear region of normal and cancer cells, indicating the subcellular localization of the enzymes in the Golgi apparatus. The prevalence of positive staining for T1 and T2 expression in colorectal cancer was significantly higher than that in normal epithelium (P 〈 0.05). However, the difference in staining grades between cancer and normal tissues varied in each patient. These results indicate that there is variability in the expression patterns of GalNAc transferase isozymes in normal and cancerous cells colorectal among individuals.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s005350070021
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  • 4
    Digitale Medien
    Digitale Medien
    Gastric carcinoid tumors in a brother-sister occurrence, with special reference to ultrastructural features of endocrine granules (1997)
    Springer
    Medical molecular morphology 30 (1997), S. 228-234 
    Details
    ISSN: 1860-1499
    Schlagwort(e): Gastric carcinoid tumors ; Familial occurrence ; Electron microscopy ; Endocrine granules
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Our report concerns gastric carcinoid tumors in a man and his younger sister who had no endocrine symptoms. The tumors in both cases were multiple, located in the corpus, and showed no significant differences in light microscopic and immunohistochemical examination. In electron microscopic observation, the endocrine granules of tumor cells were roughly classified into four types: granules with fine granular content with low electron density, irregularly striped granules with medium electron density, concentrically laminated or regularly striped granules, or smaller and almost uniformly high electron-dense granules in which it was difficult to recognize the internal structure. From the sequential morphological changes of the granules, we have considered that each type of granule reflects various stages of granulogenesis, although the possibility that they are distinct and contain different hormones or chemical mediators is not absolutely ruled out.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01545775
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