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  • 1
    Digitale Medien
    Digitale Medien
    Long-term observation of chronic subsutaneous administration of lisuride in the treatment of motor fluctuations in parkinson's disease (1992)
    Springer
    Journal of neural transmission 4 (1992), S. 291-301 
    Details
    ISSN: 1435-1463
    Schlagwort(e): Parkinson's disease ; continuous lisuride infusion ; motor fluctuations
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Twenty-nine patients with advanced Parkinson's disease were treated with subcutaneous lisuride infusion in addition to a basic therapy consisting of levodopa + PDI in all, and deprenyl in some patients. At the time of the report, 13 patients are still receiving lisuride infusion after 5–36 months, while 16 have dropped out after 0.5–30 months one because of psychosis, three because of insufficient efficacy, three due to death unrelated to treatment, three because of difficulties in handling the pump as outpatients, and six for other reasons. “Off”-periods and parkinsonian disability in “off” and in “on” were reduced significantly. These improvements remained constant throughout the observation period. Once the optimal dose regimen is established, only minor adjustments of the doses of lisuride and levodopa are required in the individual case.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02260078
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