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  • 1
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Objective To assess the effectiveness of second trimester 24-hour ambulatory blood pressure measurement as a screening test for pre-eclampsia.Design Prospective interventional study.Setting John Radcliffe Maternity Hospital, Oxford, and Queen Charlotte's and Chelsea Hospital, London.Subjects One hundred and sixty-two normotensive nulliparous women recruited at hospital booking clinics.Intervention Ambulatory blood pressure was measured at 18 and 28 weeks gestation using the TM2420 monitor.Main outcome measure The development of pre-eclampsia.Results Awake systolic and mean arterial pressures were significantly increased (P〈0.02) at 18 weeks in those who later developed pre-eclampsia. Those differences were more apparent at 28 weeks at which time the diastolic pressure was also increased (P〈0.01). At both stages of gestation the higher readings were sustained during sleep so that the awake-sleep differences were similar in relation to each outcome. The group with incipient pre-eclampsia had a significantly faster heart rate at both 18 and 28 weeks (P〈0.002) The sensitivity in predicting pre-eclampsia for a mean arterial pressure of 85 mmHg or greater at 28 weeks was 65%, with a positive predictive value of 31 %. The sensitivity and positive predictive value for a test combining a mean arterial pressure of 85 mmHg or greater and a heart rate of 90 bpm or greater were 53% and 45%, respectively.Conclusion Although second trimester ambulatory blood pressure is significantly increased in women who later develop pre-eclampsia, the predictive values for blood pressure alone are low. The efficiency of the test is increased by combining the awake ambulatory heart rate and blood pressure measurement together. If an effective method for preventing pre-eclampsia becomes available (commencing at 28 weeks gestation), then awake ambulatory blood pressure and heart rate may have some clinical value as a screening test.
    Materialart: Digitale Medien
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 24 (1994), S. 0 
    ISSN: 1365-2222
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: An increasing number of studies have implicated passive smoking as a definite threat to non-smokers' health. Self-reports of smoking status may not always be reliable, particularly in situations where the smoker feels under pressure to give up smoking. In this study questionnaire and salivary cotinine, an objective measure of nicotine exposure, were studied in asthmatic and age-matched control children. We have consequently developed a sensitive assay for cotinine using high performance liquid chromatography (HPLC) to quantitate environmental tobacco smoke (ETS) exposure in a group of 5- to 7-year-old asthmatic and control children. We chose to use mixed unstimulated saliva collected by absorption into dental rolls in the mouth for 5 min. Our modified extraction procedure was highly reproducible with a 〉90% retrieval rate of cotinine from spiked saliva. The parents were asked to fill in a questionnaire on atmospheric pollutants to obtain an estimate of declared ETS exposure in the home. Results showed that 31% of the asthmatic patients were exposed to ETS, according to the parents, but by HPLC 69% had been so exposed (n=19). From the control group the figures were 40% and 50% of patients, respectively. Therefore, an objective assessment is essential as ETS is more ubiquitous than is apparent from the questionnaire alone. Finally, in this small number of individuals our objective assessment demonstrates that ETS exposure is more prevalent in asthmatic children (69%) than age-matched controls (51%).
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Weed research 36 (1996), S. 0 
    ISSN: 1365-3180
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: The spatial variability of weeds within fields was studied for six sets of count data. Heterogeneity for a given mean population density was measured using the variance of the counts between sample units at different locations; relatively large values of sample variance imply aggregation. The dependence of variance on mean was measured using the relationship known as Taylor's power law, ubiquitous in animal ecology but seldom used for plant populations. This was fitted to an extensive set of plant counts and 69 estimates of its parameters b, an index of aggregation, and log10a were computed. Estimates were corrected for bias when the number of samples was small. Overall, b varied between 1.32 and 2.61, and log10a varied between -0.85 and 1.58. agreeing well with previous estimates for both plant and animal populations. Parameter estimates varied with sample size and spatial sample scale, but unpredictably. Parameter values when species counts were combined were compared with individual species analyses. Knowledge of the likely range of these parameters for weed populations provides an important basis for future modelling of the relationship between weed density and crop yield loss.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Oecologia 112 (1997), S. 543-550 
    ISSN: 1432-1939
    Schlagwort(e): Key words Nonlinear dynamics ; Time series analysis ; Models ; Aphids
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Density-dependent factors, such as population growth rate and migration, influence dynamic behaviour in ecological models. Temperature, an abiotic and density-independent factor, is also an important determinant of insect population growth. We investigated the endogenous dynamics of a density-dependent response-surface model that included temperature, based on time series for two aphid species. We investigated the effects of temperature and random noise on the model dynamics. In most cases, an increase in temperature resulted in a higher predicted equilibrium density; it could induce complex dynamics. Noise at the level of the natural variation in temperature resulted in extinctions in some models. Our results from these models indicate that aphid populations might become more abundant, and less stable in some circumstances, if there is climate warming.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 330 (1985), S. 179-183 
    ISSN: 1432-1912
    Schlagwort(e): Visceral distension reflex ; Codeine ; Morphine ; Quaternary opiates ; Peripheral analgesia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary 1. Distension of the proximal ileum by elevation of the intraluminal pressure, caused a transient, reflex fall in blood pressure of urethane-anaesthetised rats. The threshold intraluminal pressure required to evoke a reflex response was increased by codeine, but not by the quaternary opiate agonist N-methylmorphine. 2. The magnitude of the reflex hypotension was decreased by codeine, morphine and N-methylmorphine. The quaternary opiate antagonist N-methylnalorphine reduced the effects of N-methylmorphine, but not those of codeine or morphine. Codeine-induced inhibition of reflex depressor responses was reduced by pretreatment with naloxone. 3. Bilateral vagotomy caused a significant decrease in effects of codeine on the threshold, but not the magnitude, of reflex depressor responses. Furthermore N-methylnalorphine antagonised both codeine- and morphine-induced inhibition of depressor responses following transsection of the vagus nerves. 4. Effects of opiates on the threshold for the reflex appear to be centrally mediated and to require an intact vagal innervation. The magnitude of depressor responses is largely independent of vagal innervation and may be influenced by opiates acting via peripheral mechanisms.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    facet.materialart.
    Unbekannt
    New Haven, Conn., etc. : Periodicals Archive Online (PAO)
    Religious Education. 24 (1929:Jan./Dec.) 782 
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 7
    facet.materialart.
    Unbekannt
    New Haven, Conn., etc. : Periodicals Archive Online (PAO)
    Religious Education. 24 (1929:Jan./Dec.) 784 
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 8
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] The UK Farm-Scale Evaluations (FSE) compared the effects on biodiversity of management of genetically modified herbicide-tolerant (GMHT) spring-sown crops with conventional crop management. The FSE reported larger weed abundance under GMHT management for fodder maize, one of three crops ...
    Materialart: Digitale Medien
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  • 9
    Digitale Medien
    Digitale Medien
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 35 (1979), S. 2550-2553 
    ISSN: 1600-5740
    Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Thema: Chemie und Pharmazie , Geologie und Paläontologie , Physik
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Entomologia experimentalis et applicata 80 (1996), S. 87-89 
    ISSN: 1570-7458
    Schlagwort(e): secondary plant metabolites ; isothiocyanates ; variability ; plant genetics ; Chrysomelidae
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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