ISSN:
1420-9071
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Compared to control, kidney slices from rats undergoing glycerol-induced ATN produce less ammonia from glutamate, but show no difference when glutamine is substrate. However, gluconeogenesis from glutamine, like glutamate, is decreased in acute tubular necrosis (ATN). We conclude that renal ammoniagenesis is influenced by ATN. Glycerol-induced ATN causes a relative increase in glutamine deamidation and a decrease in glutamate deamination.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01964090
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