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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 57 (1978), S. 133-136 
    ISSN: 1432-2072
    Keywords: Rhesus monkeys ; Ethanol reinforcement ; Ethanol concentration ; Blood ethanol level ; Ethanol drinking ; Fixed-ratio schedules ; Intoxication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Ethanol deliveries maintained fixed-ratio (FR) responding of three rhesus monkeys during daily 3-h sessions. At FR values of 8 or 16, ethanol concentration was varied in the sequence 0 (water), 8, 11.3, 16, 22.6, 32, 8, and 0% (w/v). As the ethanol concentration increased, number of liquid deliveries decreased, although intake of ethanol (g/kg/session) increased somewhat. Blood ethanol levels were usually greater than 200 mg% and occasionally greater than 300 mg%.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 59 (1978), S. 225-229 
    ISSN: 1432-2072
    Keywords: Rhesus monkeys ; Etonitazene HCl ; Etonitazene concentration ; Etonitazene reinforcement ; Fixed-ratio schedules ; Etonitazene drinking ; Oral self-administration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Drinking of etonitazene HCl was studied in three rhesus monkeys during daily 3-h sessions. As the drug concentration was increased, the number of liquid deliveries decreased, and etonitazene intake (μg/kg body weight) increased. As fixed-ratio (FR) requirements were increased, rate of responding increased, and liquid deliveries slightly decreased. When water was substituted for the drug, there was a large increase in responding for several sessions, followed by a slow decline to low rates. When etonitazene was reintroduced, responding abruptly increased to previous drug levels. These data suggest that etonitazene can serve as a positive reinforcer when taken orally by rhesus monkeys.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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