ISSN:
1662-8985
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
In order to construct an intelligent functional nano-interface, the self-organized structureof Langmuir-Blodgett (LB) film was investigated by atomic force microscopy (AFM). As a buildingblock, a monodisperse loop-helix-helix triblock copolypeptide containing the helix of whichhydrophobic L-leucine residues align on a single face, “leucine zipper”, was synthesized byrecombinant DNA techniques with a designed amino acid sequence. AFM observation on the surfacestructure of LB films constructed at surface pressures of 2, 5 and 18 mN/m revealed that structuraltransition from ring- or disk-like aggregations to a lane-like fabrication occurred with compression ofthe copolypeptide membrane on the water of pH 4. The leucine zipper in the copolypeptide wassuggested to perform as an important basis for nanostructure formation through a hydrophobicinteraction. Exploitation of the recognition and specific binding sites in the copolypeptide will allowthe self-assembling mechanism of the copolypeptide to be developed to a novel nano-template
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/39/transtech_doi~10.4028%252Fwww.scientific.net%252FAMR.11-12.635.pdf
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