ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
15N NMR Studies of the Tautomeric Equilibrium of N-Monosubstituted Amidines and of N,N′-Diphenylguanidine15N NMR data are reported for tautomeric N-monosubstituted amidines 1a and b and for N,N′-diphenylguanidine (6). In order to elucidate the position of the tautomeric equilibrium, the nitrogen resonances of the salts of 1a, b and 6 were also determined. For comparison, chemical shifts δ15N were measured of non-tautomeric amidines 2 - 5. The preferred tautomers for N-phenylbenzamidine (1a) and for 6 have the C=N double bond conjugated with the phenyl group. Replacement of an NH proton with an alkyl group, as in 1b, has little effect on the tautomeric equilibrium of amidines.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19861190331
