ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
N, N′-Bis(aminomethylidene)thioureas 1 react with electron acceptor substituted methyl halides 2 under the formation of 2-formamidinothiazoles 4. The reaction of N-(3-aminothioacryloyl)-formamidines 5 with substituted methyl halides 2 gives either 2-formamidinothiophenes 7 or 2-aminovinylthiazoles 8. The 8 can be hydrolysed to corresponding 2-hydroxyvinylthiazoles 9. 2-Aminovinylthiazoles 11 bearing primary amino groups are obtained by transamination of the N-(3-aminothioacryloyl)-formamidines 5 and subsequent reaction of the resulting 10 with substituted methyl halides 2.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19853270313