ISSN:
0025-116X
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
In order to clarify the arrangement of sulfated poly(vinyl alcohol) (PVS) chains about the α-helical poly(L-lysine) (PLL) chain in the previously reported complexes of PLL/46 mole-% sulfated poly(vinyl alcohol) (PVS-46) and PLL/PVS-95, induced circular dichroism was studied on PLL/PVS/acridine orange (AO) complexes in acidic aqueous solution. A positive ellipticity, [θ], of ca. 3 400 deg·cm2·dmol-1 at 465 am and small negative values of [θ] at 435 and 510 nm indicated a right-handed super helical arrangement of AO molecules about the right-handed α-helix of PLL, where PVS chains were intercalated. The amount of AO molecules responsible for the induced CD was estimated as low as a few mole-%. Taking into consideration the arrangement of ε-amino groups of the right-handed α-helical PLL and the distance among the neighboring ε-amino groups on the radial projection of the helix, the PVS chain segments could be arranged both in the right-handed and in the left-handed superhelices about the right-handed α-helix of PLL. In cases of the PLL/PVS-25/AO and PLL/PVS-30/AO complexes, no induced CD and a quite weak CD were obtained, resp., being consistent with random coil conformation of PLL in the PLL/PVS-25 and PLL/PVS-30 complexes mentioned previously.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/macp.1980.021810117
