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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 49 (1971), S. 108-110 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei einer Patientin mit einer reticulocytogenen lipophagen Granulomatose in Unterhautfettgewebe und Lunge sowie zwei Patientinnen mit Mamma-Carcinom wurden im Tumorgewebe die Aktivitäten folgender Enzyme bestimmt: G-6-PDH, 6-PGDH, HK, PFK, PK, GDH, GK, MDH, GPM, GPT, GOT und GluDH. In Übereinstimmung mit der Literatur fanden wir in beiden Geweben ein tumorspezifisches Enzymmuster. In den Retikuloseknoten ließ sich darüberhinaus eine deutlich meßbare Aktivität der Glycerokinase nachweisen. Die „Michaelis-Konstante“ für Glycerin unterschied sich nicht von dem für Lebergewebe angegebenen Wert. Gut meßbare Aktivitäten dieses Enzyms sind bisher nur für Leber- und Nierengewebe angegeben worden.
    Notes: Summary The activities of the following enzymes were determined in a patient showing reticulo-cytogenous lipophagic granulomatosis in her subcutaneous adipose tissue and the lungs, as well as in two patients with carcinoma of the breast: G-6-PDH, 6-PGDH, HK, PFK, PK, GHD, GK, MDH, GPM, GPT, GOT and GluDH. We found a tumor-specific enzyme pattern in both tissues, a finding which is in accord with the results published in the literature. Furthermore, a well measurable glycerokinase activity in the reticulo-cytogenous lipophagic granulomas could be demonstrated as well. The Michaelis-Menten constant for glycerol was not different from the values found in hepatic tissue. So far, these enzymatic activities had been found to be easily assessable in liver and kidney tissue only.
    Type of Medium: Electronic Resource
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