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Buformin concentrations in a case of fatal lactic acidosis (1981)

Verdonck, L. F. ; Sangster, B. ; Heijst, A. N. P. ; [et al.]

Springer

Diabetologia 20 (1981), S. 45-46

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ISSN: 1432-0428

Keywords: Lactic acidosis ; plasma buformin concentration ; tissue buformin concentration ; biguanides

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary A fatal case of lactic acidosis in a 84 year old diabetic woman taking buformin is reported. Buformin concentrations in serum, other body fluids and tissues were measured by gas chromatography. Serum buformin concentration at admission was 5.5 mg/1. Postmortem concentrations were: in serum 3.2mg/l; in lung 2.8mg/kg wet weight; in heart 3.0mg/kg; in pericardial fluid 3.5 mg/1; in liver 5.2 mg/kg; in bile 6.3 mg/1; and in kidney 98 mg/kg.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00253815

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