ISSN:
1432-1041
Keywords:
bronchodilator
;
ipratropium
;
fenoterol
;
combination
;
chronic bronchitis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary This paper reports a study of the bronchodilator effects of doses of the beta2 agonist fenoterol and the muscarinic blocker ipratropium suitable for administering in combination as a standard dose of two discharges from a single metereddose pressurised aerosol. In 12 middle-aged bronchitics who had already been shown to respond to both types of drug the combination was almost always a little (6% on average) more effective than either drug singly. It is possible that an equal or better effect could have been obtained if fenoterol or perhaps ipratropium had been given alone in an individually determined maximally effective dose.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00563114
