ISSN:
1432-1416
Keywords:
Key words: Cell division
;
Stability
;
Gamma distribution
;
Measure
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Mathematics
Notes:
Abstract. This paper couples a general d-dimensional (d arbitrary) model for the intracellular biochemistry of a generic cell with a probabilistic division hypothesis and examines the consequence of division for stability of cell function and structure. We show rather surprisingly that cell division is capable of giving rise to a stable population of cells with respect to function and structure even if, in the absence of cell division, the underlying biochemical dynamics are unstable. In the context of a simple example, our stability condition suggests that rapid cell proliferation plays a stabilizing role for cellular populations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002850050148
