ISSN:
1432-0533
Keywords:
Organic Mercury Compound
;
Late Pathological Changes in Peripheral Nerves
;
Electron Microscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Wistar strain of male rats of 100–110 g were used, 5 for an experimental and 5 for control group. 1 mg of organic mercury (methyl methylmercuric sulfide: CH3HgSCH3) was given by mouth each day for 10 days (total dose 9–10 mg) to the experimental group. 600 days afterwards the experimental and control rats were killed. Only the peripheral nerves showed changes, small myelinated nerve fibres with thick myelin sheaths in groups. Around these fibres occurred extremely small myelinated nerve fibres and isolated large unmyelinated fibres, and appeared to be regenerated fibres. Destruction of myelin sheaths and cavity formation in the axons were observed in these fibres. The changes in the axons were remarkable at the nodes of Ranvier.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00685320
