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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 220 (1975), S. 123-138 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Bestimmung der Chromosomenzahlen in 9 Dysplasien, 25 Carcinomata in situ, 4 Mikrocarcinomen und 16 Plattenepithelcarcinomen (mindestens Stadium Ib) der Cervix uteri ergab, daß sich die Gruppen der Carcinomata in situ, der Mikrocarcinome und der fortgeschrittenen Plattenepithelcarcinome aufgrund von numerischen Chromosomenanomalien nicht prinzipiell voneinander unterscheiden lassen. Auffällig ist lediglich ein etwas häufigeres Vorkommen von Zellen im triploiden Bereich bei invasiven Carcinomen. Die Gruppe der Dysplasien zeigt generell geringere numerische Chromosomenanomalien als die drei anderen Gruppen; Chromosomengewinne sind in dieser Gruppe selten, Chromosomenverluste scheinen ein häufiges Ereignis zu sein.
    Notes: Summary Analysis of chromosome numbers of 9 dysplasias, 25 carcinomas in situ, 4 carcinomas in situ with microinvasion and 16 invasive squamous carcinomas (at least clinical stage Ib) of the cervix uteri showed that the numerical deviations of the chromosome number cannot be differentiated in principle between the carcinoma in situ, carcinoma in situ with microinvasion and invasive squamous carcinoma groups. The only remarkable finding is that cells in the triploid region appear somewhat more frequently in the invasive squamous carcinoma group. The dysplasia group has in general less numerical chromosome deviations than the other three groups. Chromosome gains seldom occur in this group, chromosome losses appear to be a more frequent event.
    Type of Medium: Electronic Resource
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