ISSN:
1432-2099
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Physics
Notes:
Summary A technique for maintaining mammalian ovaries in organ culture is described. Ovaries of rats, mice, monkeys and humans have been maintained in a histologically normal condition for up to 20 days in culture, during which many were X-irradiated. The doses of X-rays required to destroy all the primordial oocytes in organ cultures are similar to those reported forin vivo studies. The human foetal ovary is resistant to X-irradiation. Some oocytes survive for 7 days following exposure to 4000 R in organ culture. The radiation sensitivity of the human ovary is discussed: it would appear that it is amongst the most resistant to oocyte-killing known.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01403867