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Experimental studies on the spitting cobra ophthalmia (Naja nigricollis) (1985)

Grüntzig, J. ; Lenz, W. ; Berkemeier, B. ; [et al.]

Springer

Graefe's archive for clinical and experimental ophthalmology 223 (1985), S. 196-201

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ISSN: 1435-702X

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Experimental studies were conducted to investigate the clinical and morphological effects of various doses ofNaja nigricollis venom (0.1–5.0 mg) on the eyes of rabbits. Our findings suggest that in the early stage of the ophthalmia caused by the spitting cobra, specific fractions of the venom are responsible for the nitrogen mustardlike effect. However, the further course seems to be determined by liberated inflammation mediators like prostaglandins and leukotrienes.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02174059

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