ISSN:
1432-1335
Keywords:
Human T-cell leukaemia virus
;
Transformation
;
Lymphocyte
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Human adult peripheral blood lymphocytes were successfully immortalized by co-cultivation with irradiated autologous and homologous T-cell lines harbouring human T-cell leukaemia virus-I (HTLV-I). The efficiency of transformation was the same in both cases. The participation of alloantigen stimulation in co-cultivation procedures is discussed, and it is stressed that factors other than alloantigen stimulation might be required for the efficient immortalization of human T-lymphocytes in vitro by HTLV.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00402508