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  • 1
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Orale Gaben von N-Äthyl-N′-nitro-N-nitrosoguanidin in einer Konzentration von 91 μg/ml im Trinkwasser durch 12 Monate führten bei Hamstern zur Bildung von Adenocarcinomen des Drüsenmagens und des Zwölffingerdarmes. 6 Adenocarcinome des Drüsenmagens und 6 Adenocarcinome des Duodenums wurden bei 13 Tieren gefunden, die nach mehr als 36 Wochen starben. Unter diesen Versuchsbedingungen entstanden Sarkome weder im Drüsenmagen noch im Duodenum.
    Notes: Summary Oral administration of N-ethyl-N′-nitro-N-nitrosoguanidine to hamsters at a concentration of 91 μg/ml in the drinking water for 12 months produced adenocarcinomas of the glandular stomach and the duodenum. 6 adenocarcinomas in the glandular stomach and 6 adenocarcinomas in the duodenum were found in 13 animals which died after more than 36 weeks. No sarcoma developed in the glandular stomach or duodenum on ENNG administration.
    Type of Medium: Electronic Resource
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