ISSN:
1433-8580
Keywords:
Adrenal irradiation
;
131I-6β-iodocholesterol
;
Rabbits
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Administration of high doses of131I-6β-iodocholesterol to rabbits is followed by marked size reduction of the adrenal glands with concomitant changes of the histological structure and with a decrease of serum cortisol. Stimulation of131I-6β-iodocholesterol uptake into the adrenals by additional administration of ACTH had only a minor additional effect on adrenal weight. However, with further accumulation of labeled cholesterol in the adrenals the radioactivity was reduced in blood, urine, and the ovaries.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01851618