ISSN:
1432-0827
Keywords:
Fracture Healing
;
Glucose 6-phosphate
;
Dehydrogenase
;
Glutathione
;
Microdensitometry
;
Cytochemistry
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
,
Physics
Notes:
Summary The activity of pentose-shunt dehydrogenases is very low in periosteal cells of normal rat metatarsals, but increases one day post-fracture and rises linearly over the next two days. By four days postfracture, the distribution of this activity along the bone shows two centres of high activity: the first in the region of proliferation to form callus and the second at the site where new bone is first seen, one day later. The high rate of generation of NADPH would be expected to reduce glutathione; reduced glutathione has been shown to inhibit alkaline phosphatase activity in these cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02012769
