ISSN:
0018-019X
Schlagwort(e):
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
3:3-Disubstituted 2,6-dioxo-piperidine derivatives can be prepared by means of a Michael condensation of disubstituted acetic acid nitriles or acetic acid esters with acrylonitrile or acrylic acid esters, followed by saponification and ring closure. Of the aminoalkylated phenyl-dioxo-piperidines described the 3-diethylamino-ethyl-3-phenyl-2,6-dioxo-piperidine has an especially strong and specific parasympathicolytic action. For purposes of comparison some pyrrolidine and hexamethyleneimine compounds were also prepared.
Zusätzliches Material:
14 Tab.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/hlca.19520350420