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Digitale Medien

Lack of effect of haemodialysis on mebendazole kinetics: Studies in a patient with echinococcosis and renal failure (1984)

Allgayer, H. ; Zähringer, J. ; Bach, P. ; [weitere]

Springer

European journal of clinical pharmacology 27 (1984), S. 243-245

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Details

ISSN: 1432-1041

Schlagwort(e): mebendazole ; haemodialysis ; echinococcosis ; pharmacokinetics ; protein binding

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Medizin

Notizen: Summary The effect of haemodialysis on mebendazole kinetics has been studied in a patient receiving both mebendazole therapy and haemodialysis. The procedure of haemodialysis did not influence the plasma concentration — time profiles or the mean daily plasma levels. The arterio-venous difference in the dialyser was negligible and no mebendazole could be detected in the dialysate. Protein binding of mebendazole was 90% before dialysis and 88% during dialysis and not significantly different from the binding in patients without renal disease (91.4±1.9%, n=22).

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00544053

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