ISSN:
0306-042X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Gas chromatography mass spectrometry has been used to study the reaction between a range of aromatic, alicyclic and aliphatic sulphate esters and three perfluoroacylating reagents, viz. trifluoroacetic, pentafluoropropionic and heptafluorobutyric anhydride. Aromatic sulphates were found to react readily, when treated with a 1:1 mixture of a perfluoroacid anhydride and dry ethyl acetate, to form the perfluoroester derivative of the parent phenol in quantitative yield. Non-aromatic sulphates, on the other hand, gave a variety of products. A mechanism is proposed for the one-step derivatization of aromatic sulphates and the potential of the procedure for the analysis of sulphate conjugates by mass spectrometry is discussed.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bms.1200060209