ZIB

Treffer pro Seite

Treffer 1 - 1 | 1 Treffer

Alles auswählen Exportieren

Digitale Medien

Use of buildup and energy-minimization procedures to compute low-energy structures of the backbone of enkephalin (1985)

Vásquez, Max ; Scheraga, Harold A.

New York : Wiley-Blackwell

Biopolymers 24 (1985), S. 1437-1447

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 0006-3525

Schlagwort(e): Chemistry ; Polymer and Materials Science

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie

Notizen: A method for the conformational analysis of a polypeptide, using buildup and energy-minimization procedures, is presented. It has been tested by computing the conformation of the backbone of Met-enkephalin, a pentapeptide, and comparing the results with those obtained by a Monte Carlo procedure. The agreement between the results of the two different methods indicates that the multiple-minima problem has been overcome for the enkephalin molecule (with fixed side-chain conformations). The buildup procedure uses objective criteria, which should be applicable to the conformational analysis of polypeptides much larger than enkephalin. With anticipated advances in supercomputers, the methodology should be applicable to proteins.

Zusätzliches Material: 6 Tab.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/bip.360240803

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Treffer 1 - 1 | 1 Treffer