ISSN:
0006-3525
Schlagwort(e):
RNA
;
pseudoknot
;
Turnip Yellow Mosaic Virus
;
Mouse Mammary Tumor Virus
;
Beet Western Yellows Virus
;
Simian Retrovirus type-1
;
Hepatitis Delta Virus
;
translational frameshifting
;
ribozyme
;
nmr
;
x-ray diffraction
;
Chemistry
;
Polymer and Materials Science
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Recently, several high-resolution structures of RNA pseudoknots have become available. Here we review the progress in this area. The majority of the structures obtained belong to the classical or H-type pseudoknot family. The most complicated pseudoknot structure elucidated so far is the Hepatitis Delta Virus ribozyme, which forms a nested double pseudoknot. In particular, the structure-function relationships of the H-type pseudoknots involved in translational frameshifting have received much attention. All molecules considered show interesting new structural motifs. © 1999 John Wiley & Sons, Inc. Biopoly 48: 137-153, 1998
Zusätzliches Material:
13 Ill.
Materialart:
Digitale Medien
