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Digitale Medien

Experimental optimization of fed-batch culture for poly-β-hydroxybutyric acid production (1997)

Lee, Jung Heon ; Hong, Juan ; Lim, Henry C.

New York, NY [u.a.] : Wiley-Blackwell

Biotechnology and Bioengineering 56 (1997), S. 697-705

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Details

ISSN: 0006-3592

Schlagwort(e): poly-β-hydroxybutyric acid ; Alcaligenes eutrophus ; fed-batch culture ; high cell density culture ; optimization ; Chemistry ; Biochemistry and Biotechnology

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: The optimal feed rate profiles of glucose and ammonium hydroxide were calculated using a proposed model, and implemented for the production of poly-β-hydroxybutyric acid (PHB) by Alcaligenes eutrophus. By implementing these optimal feed rates with a high glucose feed concentration of 700 g/L and an ammonium hydroxide concentration of 7%(w/w), it was possible to achieve a high final cell concentration of 141 g/L and a high PHB concentration of 105 g/L in 40 h of fed-batch operation. The PHB productivity was as high as 2.63 g/(L hr). © 1997 John Wiley & Sons, Inc. Biotechnol Bioeng 56: 697-705, 1997.

Zusätzliches Material: 7 Ill.

Materialart: Digitale Medien

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