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Production of oxytetracycline and rifamycins B and SV with cells immobilized on glass wool (1994)

Farid, M. A. ; El Diwany, A. I. ; El Enshasy, H. A.

Berlin : Wiley-Blackwell

Acta Biotechnologica 14 (1994), S. 67-74

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ISSN: 0138-4988

Keywords: Life Sciences ; Life Sciences (general)

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Process Engineering, Biotechnology, Nutrition Technology

Notes: The antibiotic producing microorganisms Streptomyces rimosus PFIZER 18234-2 and Amycolatopsis mediterranei CBS 42575 were immobilized in glass wool for the production of oxytetracycline and rifamycins B and SV. The growth of the immobilized cells was dependent on the type of the microorganism and on the amount of glass wool as well. After 5 exchanges of the medium, 530 mg O.T.C., 2138 mg rifamycin B and 8672 mg rifamycin SV were maintained. The periodic batch culture was continued for 20 days.

Additional Material: 2 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/abio.370140112

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