ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
Normally, the size of pancreatic acini is remarkably decreased after birth in the rat.Administration of water or milk on day 21 of gestation resulted in decreased acinar size a day later in intact fetuses and in fetuses decapitated immediately after administration of water or milk. The same treatments of premature newborn rats obtained by Caesarean section on day 22 of gestation induced similar effects a day later On the other hand, in starved Caesarean newborn rats, there were no histologic changes in acini. In spontaneous newborn rats which were allowed to suckle maternal milk and then starved for one day, there was an increase in acinar size as compared with that of 2-day-old normal rats.These results suggest that the fetal pancreatic acini at least near term (on day 21 of gestation) can respond to some signals conveyed from digestive tracts which have responded to exogenous stimuli, that the brain during fetal days does not play any role in digestive tract-pancreatic acini interrelations in secretion of zymogen granules and that the neonatal decrease in acinar size is caused by the intake of maternal milk.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091800404
