ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis and X-Ray Structure of (E)-α-(Trifluoromethyl)stilbeneStarting from benzyltriphenylphosphonium chloride and ω,ω,ω-trifluoroacetophenone α-(trifluoromethyl)stilbene was prepared with 91% yield with a phase transfer-catalyzed Wittig reaction with solid KF but without bases. The isolated isomer was found by X-ray structure analysis to have the thermodynamic preferred (E)-configuration. For this configuration it was determined a torsion angle of 71.3° between the two cis-configurated phenyl rings because of steric hindrance. AH⃜F hydrogen bridge (distance: 223.8 pm) stabilizes the (E)-isomer.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19801131030
