ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Reaction of 2,2-Dichloro-1-methyl-3-phenylcylopropanemethanol Tetrahydropyranyl Ether with Butylliuthium/CO2 and Subsequent Reactions of the ProductsWhile the title reaction starting from 2a followed by acidic work-up affords only the α-chlorolactone 1 with low yield, alcaline work-up and addition of dimethyl sulfate lead to a mixture of the esters 2b and c and the chlorocyclopropene 3a. From 2b/c with KOtBu the cyclopropene ester 3f is formed. Hydrolysis of 3a (↠3d), 3f (↠3g), and 2b (↠2d) gives the hydroxymethyl compounds, while 2c is lactonized directly to 1.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19841171218