ISSN:
0170-2041
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Attempts on N-Amination of AlkaloidsSpiro[cyclohexane-1,3′-oxaziridine] (1) and ephedrine (4) react with N-N-bond formation to give the cyclic hydrazine derivative 6. Compound 1 also reacts with the hydroxytetrahydropapaverine 9a with N-N-bond formation; the reaction product undergoes C-C-cleavage under the action of acid and forms the hydrazonium salt 10.
Notes:
Spiro[cyclohexan-1,3′-oxaziridin] (1) reagiert mit Ephedrin (4) unter N-N-Knüpfung zu dem cyclischen Hydrazinderivat 6. Das Hydroxytetrahydropapaverin 9a reagiert mit 1 ebenfalls glatt unter N-N-Knüpfung; das Reaktionsprodukt erleidet durch Säure unter C-C-Spaltung Umlagerung zum Hydrazoniumsalz 10.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.198319830616
