ISSN:
0170-2041
Keywords:
β-Carbolines
;
1-Ethyl-β-carboline
;
Harman
;
9-Formylharman
;
Alkaloids
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
β-Carboline Alkaolids, IV. - Synthese of 1-Alkyl-β-carbolines and Structure Revision of Lycii Alkaloid IPalladium-catalyzed coupling reactions of 1-chloro-β-carboline (1) with triethylborane and trimethylaluminum give the alkaloids 1-ethyl-β-carboline (2) and harman (5). The intermediate 4 on treatment with ethyl formiate gives 9-formylharman (6). Comparison of the spectroscopic data shows, that lycii alkaloid I does not have the structure 6, but is identical with the alkaloid 1-acetyl-β-carboline (7).
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1993199301218
