ISSN:
0941-1216
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
7-Methyloctahydroacridines 7a-d were obtained by a one-pot imine condensation/Lewis acid-catalyzed cyclization from aniline derivatives 5a-d and aldehyde 6. Only those compounds 7 could be oxidized with DDQ to the corresponding octahydroacridine-7-carbaldehydes 9, which bear a meta-chloro or bromo substituent (with respect to the methyl group) in addition to the para-amino group (i.e. 7c,d → 9c,d). Aldehyde 9c was further converted to the novel tripodand 11 which was characterized by X-ray crystal structure analysis.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19983400408