ISSN:
0538-8066
Keywords:
Chemistry
;
Physical Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The effects of mixed CH3CN(SINGLEBOND)H2O solvents on rates of aminolysis of ionized phenyl salicylate, PS-, reveal a nonlinear decrease in the nucleophilic second-order rate constants, knms, (for aminolysis) with increase in the content of CH3CN until it becomes ∼50%, v/v. The values of knms remain almost unchanged with change in the CH3CN content within 50 to 70 or 80%, v/v. The effects of mixed CH3CN(SINGLEBOND)H2O solvents on pKa of leaving group, phenol, and protonated amine nucleophile have been concluded to be the major source for the observed mixed solvent effects on knms. © 1998 John Wiley & Sons, Inc. Int J Chem Kinet: 30: 301-307, 1998.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
