ISSN:
0018-019X
Schlagwort(e):
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Synthesis of Macrocyclic Lactams from Ketones by Ring Enlargement ReactionA general synthesis of N-unsubstituted and N-alkyllactams of general structure III is given. Starting materials for this conversion are the aldehydes of general structure I which, by reductive amination, are converted to the corresponding amines II. Under base catalysis, the ring enlargement II→III takes place (Scheme 3).
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/hlca.19850680222