ISSN:
0018-019X
Schlagwort(e):
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Starting from 3-(benzyloxy)cyclobutane-1,1-dimethanol, 3-thyminyl- and 3-adenylcyclobutane-1,1-dimethanol were synthesized by direct introduction of the heterocycles (Scheme 1). The mono-O-substituted methoxytrityl derivatives were separately converted to octameric phosphodiesters on an aminomethyl-polystyrene carrier by the phosphotriester method. These oligomers of carba-nucleosides were prepared in order to study their annealing behaviour towards ribo- and deoxyribo-nucleic acids as well as their potential for homologous hybridization.
Zusätzliches Material:
1 Tab.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/hlca.19920750216