ISSN:
0020-7608
Keywords:
Computational Chemistry and Molecular Modeling
;
Atomic, Molecular and Optical Physics
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Seventeen different computer experiments are presented and analyzed. In each experiment a three-turn B-DNA double helix fragment interacts with a variable number of water molecules (from 60 to 1200), with a variable number of sodium ions (from 30 to 63), at one or more temperatures (280, 300, 320 K). The experiments are performed with the Monte Carlo method using quantum-mechanically derived potentials. In the analysis of the experiments we partition the water molecules (and the corresponding interactions) as being either bound or in the first solvation shell or in the groove regions relative to DNA; for the former two cases, the number of water molecules and the water interaction energy are reported for selected atoms or groups of atoms. The entire study is condensed into eight tables. The use of these tables is exemplified by considering, in detail, some of the trends emerging from these experiments. The analyses are complemented by graphical representations presented either to elucidate the very complex pattern of hydrogen bonded water molecules, or to show the statistical distributions of the oxygen and hydrogen atoms of the water molecules.
Additional Material:
25 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/qua.560220311
