ISSN:
0894-3230
Keywords:
Organic Chemistry
;
Physical Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
The reaction between 1-fluoro-2,4-dinitrobenzene and n-butylamine in toluene shows a two-step plot of kobs, values vs the initial values of the concentration of the amine. The usual base-catalysis mechanism for HF elimination from the zwitterionic intermediate hardly explains this kinetic behaviour and the kinetic effect of addition of salts (and of 2-hydroxypyridine) to the reaction mixtures at different initial values of the concentration of n-butylamine. In contrast, the kinetic behaviours are easily explained by the presence of substrate-amine (or catalyst) interactions on the pathway of the substitution reaction.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/poc.610050707
