ISSN:
0360-6376
Keywords:
Physics
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A study was conducted of the complementary base pair interactions between various pairs of electron-donor monomers, electron-acceptor monomers, homopolymers and alternating copolymers selected from the following group: (1) 9-(2-vinyloxyethyl)adenine; (2) 1-(2-vinyloxyethyl)thymine; (3) 1-(2-vinyloxyethyl)cytosine; (4) 9-(2-maleimidoethyl)adenine; (5) 6-chloro-9-(2-maleimidoethyl)purine; (6) 1-(2-maleimidoethyl)thymine; (7) 1-(2-maleimidoethyl)cytosine; (8) homopolymer of (4); (9) homopolymer of (6); (10) alternating copolymer of (2) and maleic anhydride; (11) alternating copolymer of (2) and (5); and (12) alternating copolymer of (2) and (4). By 1H-NMR, in CDCL3, the base pair interactions between (1) and (2) were shown to be hydrogen bonding, the extent of which was shown by a calculated binding constant, K = 61.81 L/mol. The nature of this interaction was conformed by IR. Neither monomer pairs (1)/(2) nor (4)/(6) exhibited hydrogen bonding in DMSO-d6. However, hydrogen bonding interaction was observed for DMSO-d6 solutions of homopolymers (8) and (9) and for alternating copolymer (12). On the basis of an upfield chemical shift of the 2- and 8-aromatic protons of ademine of (1) in D2O, a partial overlap stacking interaction is proposed. No charge-transfer interactions could be observed by UV between donor-acceptor monomer pairs.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/pol.1984.170221210
