ISSN:
1420-9071
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The male antifertility agent α-chlorohydrin (I) is metabolized by rat and boar sperm to β-chloroactaldehyde (III), β-chlorolactate (IV) and Cl− and not to the proposed active metabolite, α-chlorohydrin-1-phosphate (III). It is proposed that β-chlorolactaldehyde is produced intracellularly by a specific enzyme and that this is the metabolite responsible for the species-specific antifertility activity of α-chlorohydrin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01959850