ISSN:
1573-8353
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
Notizen:
Abstract The hydrolysis of 1-substituted 5-cyano-6-(Β-dimethylamino)vinyl-4-pyrimidinones in acidic media was studied. It was shown that the 1-benzyl derivative is converted to a mixture of α-cyano-Β-benzylamino-crotonamide and 3-cyano- and 3-carbamido-4-benzyl-amino-2-pyridones. The principal product in the hydrolysis of the 1-phenyl derivative is 3-cyano-4-anilino-5-formyl-2-pyridone. Cyclization of the latter by heating in phosphorus oxychloride leads to 3-chloro-4-cyanobenzo[b] [1, 6]naphthyr idine.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01175070