ISSN:
1573-899X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Conclusions 1. Antibodies circulating in the blood, to proteins present in the nerve tissue of the rat — 10-40-4 from the rat brain, 14-3-2, and tubulin — prevent, the development of conditioned reactions in rats in a T-shaped maze. In this case the most specific effect (a change in the number of conditioned responses and the number of errors) is exhibited by antibodies to the neurospecific protein 10-40-4 from the rat brain. 2. Antibodies circulating in the blood, to proteins that are not present in nerve tissue — 10-40-4 from human brain and bovine serum albumin — do not affect the development of conditioned responses in rats in a T-shaped maze. 3. The presence of an effect of antibodies to the protein 10-40-4 from rat brain on the process of learning in rats confirms the permeability of the blood-brain barrier to these antibodies in immunized animals.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01185368
