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99mTc complexes of 1,3-propanedithiol derivatives (1987)

Alagui, A. ; Apparu, M. ; Bardy, A. ; [et al.]

Springer

Journal of radioanalytical and nuclear chemistry 119 (1987), S. 263-273

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ISSN: 1588-2780

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering

Notes: Abstract The labelling of 1,3-n alkylpropanedithiols and of 15-/1,3-dimercapto 2-propyl/ pentadecanoic acid by99mTc has been performed by an exchange reaction with the hexachlorotechnetate ion99mTcCl 6 2− and by reduction of99mTcO 4 − with Sn/II/ in the presence of the ligand. The biological distribution of the exotechnetium complexes obtained by the latter method in mouse does not reveal a high tropism of these labelling compounds in relation to a particular tissue.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02162605

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