ISSN:
1573-4919
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Published data regarding the interaction of long-chain acyl CoA derivatives with the protein and phospholipid constituents of biological membranes is reviewed and discussed in relationship to the premise that such interactions may lead to membrane damage during pathological situations. The topics considered include: the detergent properties of long-chain CoA, the interaction with membrane-associated enzymes, biological membranes, or model membrane systems, and the binding to a soluble protein that may facilitate intracellular transport. The effects of long-chain acyl CoA on heart mitochondria and the relevance of such studies to myocardial ischemia also is emphasized.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00223520
