ISSN:
1432-0428
Keywords:
Insulin secretion
;
oral glucose
;
reflex insulin secretion
;
portal vein
;
dog
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Concentrations of immunoreactive insulin activity and of blood glucose were measured in portal and peripheral venous blood in six conscious dogs after oral administration of 1.0 g/kg glucose. Portal venous samples were obtained either by chronic catheterization or by direct puncture of the portal vein through a London-cannula. Portal venous IRI was already significantly increased 5 min after the onset of the stimulus. Peripheral venous IRI pattern reflected this early increase, but the peripheral venous blood glucose level was unchanged. The results indicate that the early peripheral venous IRI increase reflects a pancreatic insulin secretory reflex.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01219711
