ISSN:
1432-0738
Keywords:
Lipid metabolism
;
Triacylglycerol secretion
;
Free fatty acids
;
Fatty acid synthesis
;
Fluoride
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract In rats acute intoxication with 100 mg sodium fluoride/kg body wt. orally has the following metabolic consequences. Oxygen consumption is reduced by about 30–50%. Plasma free FA decrease in fed as well as in starved rats. Hepatic FA synthesis is enhanced, but TG secretion to the blood is not altered. Intravenously injected Intralipid® 20% is removed at a normal rate. In subacute intoxication (30 mg sodium fluoride/kg body wt given orally per day over 1 week) oxygen consumption is not affected. TG secretion and removal of Intralipid remain in the normal range whereas hepatic FA synthesis is increased as in acute intoxication. TG concentration in the liver, however, increases by about 30% after 1 week.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00290552
