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Digitale Medien

The duration of tolerance to the anorexigenic effect of amphetamine in rats (1975)

Götestam, K. Gunnar ; Lewander, Tommy

Springer

Psychopharmacology 42 (1975), S. 41-45

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Details

ISSN: 1432-2072

Schlagwort(e): Amphetamine ; Anorexia ; Tolerance ; Drug Dependence ; Rats

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Rats were given dl-amphetamine 16 mg/kg twice daily for 15 days. Complete tolerance to the anorexigenic effect of amphetamine developed from day 7–11. A single injection of 16 mg/kg amphetamine was given to the amphetamine pretreated rats and to saline pretreated controls at different time-points after withdrawal, and their food intakes were compared. Signs of tolerance were present at 16 but not 20 days after withdrawal.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00428823

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