ISSN:
1432-1041
Keywords:
Clonidine
;
Yohimbine
;
sleep
;
REM sleep
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Clonidine (300 µg orally) increased in man the total duration of sleep and strikingly reduced the duration of REM sleep. Yohimbine (10 mg per os) did not alter the sleep patterns in man but antagonized the effects of clonidine. These results provide evidence that an α sympathomimetic mechanism could suppress REM sleep and increased the total duration of sleep.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00562444